Congratulations to Xiaoshen Wang and Xuzichao Li! Our paper was published in Nucleic Acids Research!
Congratulations to Xiaoshen Wang and Xuzichao Li! Our paper was published in Nucleic Acids Research!
AcrIIA17 inhibits Cas9 activity through interference with Cas9-sgRNA binary complex formation. In contrast, AcrIIA18 induces the truncation of sgRNA in a Cas9-dependent manner, generating a shortened sgRNA incapable of triggering Cas9 activity.
